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Xenobiotica Volume 26, 1 Volume:- 26 Issue:- 1 Publication Date : 1st March 1996 Title: Time for a
consistent approach to preparing and culturing
hepatocytes Title: The effect of
various potential inhibitors, activators and inducers on
the N-oxidation of isomeric aromatic diazines in vitro
using rabbit liver microsomal preparations Title: N-sulfation of desipramine in rat brain Title: Hydroxyethyl cyclosporin A induces and
decreases CYP3A and p-glycoprotein levels in rat liver Title: Characterisation of in vitro metabolites
from human liver microsomes using directly coupled
HPLC-NMR: application to a phenoxathiin monoamine
oxidase-A inhibitor Title: Effects of canthaxanthin, astaxanthin,
lycopene and lutein on liver xenobiotic-metabolizing
enzymes in the rat Title: The metabolism of
2,3,5,6-tetrachloronitrobenzene (tecnazene) in the rat Title: Further studies on the urinary metabolites
of 2,4-dinitrotoluene and 2,6-dinitrotoluene in male
Wistar rats Title: Dose dependent kinetics and metabolism of
1,2-dichlorobenzene in rats: effect of pretreatment with
phenobarbital Title: Immunohistochemical assessment of human
microsomal epoxide hydrolase in primary and secondary
liver neoplasm: a quantitative approach Volume:- 26 Issue:- 2 Publication Date : 5th March 1996 Title: Enantioselective binding of casodex to the androgen receptor Authors: A. Mukherjee, L. Kirkovsky, X-T. Yao, R. C. Yates, D. D. Miller, J. T. Dalton. Pages 119-124. Title: Glucuronidation of diflunisal in liver and
kidney microsomes of rat and man Title: Biotransformation of a somatostatin analogue in
precision-cut liver and kidney slices from rat, dog and
human Title: Enzyme kinetics and substrate selectivities of
rat glutathione S-transferase isoenzymes towards a series
of new 2-substituted 1-chloro-4-nitrobenzenes Title: Quantitative structure metabolism relationships
for substituted benzoic acids in the rabbit: prediction
of urinary excretion of glycine and glucuronide
conjugates Title: Metabolism of barnidipine hydrochloride, a
potent calcium antagonist, in the rat and dog Title: HPLC-NMR identification of the human urinary metabolites of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, a nucleoside analogue active against human immunodeficiency virus (HIV) Authors: J. P. Shockcor, R. M. Wurm, L. W. Frick, P. N. Sanderson, R. D. Farrant, B. C. Sweatman, J. C. Lindon. Pages 191-202. Title: Metabolism of tetramethrin isomers in rat: III.
Stereochemistry of reduced metabolites Title: Urinary metabolic profile in rat of
1-(2-methoxyphenyl)-2-methyl-2-(3- pyridyl)-1-propanone:
a potential radioligand for functional diagnosis of
adrenal pathology Title: Identification of trimetazidine metabolites in human urine and plasma Authors: P. J. Jackson, R. D. Brownshill, G. Resplandy, B. Walther, H. R. Schwietert. Pages 223-230. Title: Plasma and urinary metabolites of efonidipine hydrochloride in man Authors: H. Nakabeppu, M. Asada. Pages 231-242. Title: Announcement 26/2 Volume:- 26 Issue:- 3 Publication Date : 22nd March 1996 Title: The distribution of
remikiren, a potent orally active inhibitor of human
renin, in laboratory animals Title: 1H and 19 F NMR spectroscopic studies on the
metabolism and urinary excretion of Mono-and
Disubstituted phenols in the rat Title: Inhibition of cyclosporine and
tetrahydrocannabinol metabolism by cannabidiol in mouse
and human microsomes Title: The excretion and metabolism of remikiren, a
potent orally inhibitor of primate renin Title: Induction of cytochrome P-450 isoenzymes in
cultured precision-cut rat and human liver slices Title: Nutritional condition affects the disposition
kinetics of albendazole in cattle Title: Identification and antimicrobial activity of
urinary metabolites of a rifamycin derivative in the dog Title: The pharmacokinetics of remikiren, a potent
orally active inhibitor of human renin, in the rat, dog
and primates Title: Metabolism of illudin S, a toxic substance of
lampteromyces japonicus: Urinary excreation of
mercapturic acids in the rat Title: Metabolism of tamsulosin in the rat and dog Title: The metabolism of drugs and other xenobiotics:
Biochemistry of redox reactions. Bernard Testa. Volume:- 26 Issue:- 4 Publication Date : 11th April 1996 Title: In vitro metabolism
of the nephrotoxicant N-(3,5-Dichlorophenyl) succinimide
in the fischer 344 rat and New Zealand white rabbit Title: Suppression of intestinal and hepatic
cytochrome P450 3A in murine toxoplasma infection.
Effects of N-acetylcysteine and Ng-monomethyl-L-arginine
on the hepatic suppression Title: Ethnic-related differences in coumarin
7-hydroxylation activities catalyzed by cytochrome P450
2A6 in liver microsomes of Japanese and Caucasian
populations Title: Role of cytochrome b5 in the oxidative
metabolism of polychlorinated biphenyls catalyzed by
cytochrome P450 Title: Liver haem metabolism in adjuvant-induced
arthritic rats Title: Reductive activation of
1,1-dichloro-1-fluoroethane (HCFC-14lb) by phenobarbital-
and pyridine-induced rat liver microsomal cytochrome
P-450 Title: Interspecies differences in Coumarin metabolism
in livermicrosomes examined by capillary electrophoresis.
Title: Study of coumarin metabolism by Chinese hamster
lung fibroblasts expressing a human cytochrome P450 using
1H-NMR. Title: Pharmacokinetics and metabolism of zamifenacin
in mouse, rat, dog and man Volume:- 26 Issue:- 5 Publication Date : 17th May 1996 Title: Topics in
Xenobiochemistry - the application of microdialysis
techniques in pharmacokinetic studies Title: Murine cytochrome P4503A is induced by
2-methyl-3-buten-2-01, 3-methyl-1-pentyn-3-01
(meparfynol), and tert-amyl alcohol Title: The formation of 2-sulfamoylacetylphenol from
zonisamide under aerobic conditions in rat liver
microsomes. Title: Lack of effect of methotrexate on the
expression of constitutive hepatic cytochromes P450 in
the male rat. Title: Pharmacokinetics of ethylene glycol Title: Application of electrospray mass spectrometry
in the identification of intact glucuronide &
sulphate conjugates of clozapine in rats. Title: Reductive metabolism plays a major role in the
disposition of the hydroxamic angiotensin converting
enzyme inhibitor idrapril calcium in the rat. Title: Effect of substituents on the metabolism of
nitracrine in the rat. Authors: I. G. C. Robertson,
T. J. Bland, B. D. Palmer. Volume:- 26 Issue:- 6 Publication Date : 19th June 1996 Title: Clofibric acid
increases the unidirectional chiral inversion of
ibuprofen in rat liver preparations. Title: Comparitive metabolism and disposition of
ethoxyquin in the rat and mouse: 1. disposition. Title: Comparitive metabolism and disposition of
ethoxyquin in the rat and mouse: 2. metabolism. Title: Sex differences in the metabolism of (+)-S-145,
a novel thromboxane A2 receptor antagonist, in the rat. Title: The fate of a thiazolidinedione antidiabetic agent in the rat and dog. Authors: G. C. Bolton, J. P. Keogh, P. D. East, F. J. Hollis, A. D. Shore. Pages 627-636. Title: Absorption, metabolism and excretion of
tamsulosin hydrochloride in man. Title: Rat liver microsomal cytochrome P450-dependent
oxidation of 3,5-disubstituted analogues of paracetamol. Volume:- 26 Issue:- 7 Publication Date : 28th June 1996 Title: Cytotoxicity and
cytoprotective activities of natural compounds. the case
of curcumin. Title: Specificity of substrate and inhibitor probes
for cytochrome P450s: Evaluation of in vitro metabolism
using cDNA-expressed human liver microsomes. Title: The comparitive hypolipidaemic and peroxisomal
effects of ciprofibrate, clofibric acid, and their
respective di-fluorocyclopropyl and 4-fluoro substituted
analogues in the rat. Title: A comparitive study of precision cut liver
slices, hepatocytes and liver microsomes from Wistar rats
using metronidazole as a model substance. Title: Molecular modelling of CYP1A subfamily members
based on an alignment with CYP102: rationalization of
CYP1A substrate specificity in terms of active site amino
acid residues. Title: Quantitation of cytochrome P450 enzymes
(CYP1A1/2, 2B11, 2C21 and 3A12) in dog liver microsomes
by enzyme-linked immunosorbent assay. Title: Major involvement of rabbit liver cytochrome
P4501A in thiabendazole 5-hydroxylation. Title: Disposition of the opioid antagonist, nalmefene, in the rat and dog. Authors: Satya S. Murthy, Chandra Mathur, Loretta T. Kvalho, Ralph A. Lessor, Jeffrey A. Wilheim. Pages 779-792. Volume:- 26 Issue:- 8 Publication Date : 23rd August 1996 Title: In vitro metabolism of a rifamycin derivative by animal and human liver microsomes, whole blood and expressed human CYP3A isoform. Authors: Tatsumasa Mae, Kazunori Hosoe, Kenji Fujii, Katsuji Yamashita, Takehiko Yamane, Takayoshi Hidaka, Takehisa Ohashi, Frank J. Gonzalez. Pages 793-802. Title: Use of fresh and cryopreserved hepatocytes to
study the metabolism of pesticides in food-producing
animals and rats. Title: Uptake, disposition, and persistence of
nonylphenol from water in rainbow trout (oncorhynchus
mykiss). Title: Nefiracetam hydroxylation by rat liver
microsomes and expressed human cytochrome P450s. Title: Modulation of rat hepatic CYP3A by nonylphenol.
Title: Interspecies scaling of tolcapone, a new inhabitor of catechol-O-methyltransferase (COMT). Use of in vitro data from hepatocytes to predict metabolic clearance in animals and humans Authors: T. Lave, S Dupin, M Schmitt, M Kapps, J Meyer, B Morgenroth, R.C. Chou, D. Jaeck, P. Coassolo. Pages 839-851. Title: Metabolism of diethyl
4-[(4-bromo-2-cyanophenyl)carbomoyl]- benzylphosphonate
in the rat. Title: The disposition of 14C-levamisole in the
lactating cow. Title: Captopril methylation in human liver and
kidney: interindividual variability. Title: Frontiers of biotransformation volume 9. Title: Biotransformations (volume 6). Title: A review of cytochrome P450: structure,
mechanism, and biochemistry (2nd edn.). Volume:- 26 Issue:- 9 Publication Date : 18th September 1996 Title: Interspecies
scaling: predicting clearance of drugs in humans. three
different approaches. Title: Metabolite kinetics of ondansetron in rat. Comparison of hepatic microsomes, isolated hepatocytes and liver slices, with in vivo disposition. Authors: J. B. Houston, Philip D. Worboys, Beverley Brennan, Alan Bradbury. Pages 897-907. Title: ß-apo-8'-carotenal, but not ß-carotene, is a
strong inducer of liver cytochromes p450 1a1 and 1a2 in
the rat. Title: Metabolism of 14C-sulphadimethoxine in swine. Title: The effect of cytochromes P450A induction and inhibition on the disposition of the cognition activator tacrine in rat hepatic preparations. Authors: Stefan Bezek, Marián Kukan, William F. Pool, Thomas F. Woolf. Pages 935-946. Title: The absorption and disposition of ranitidine
hydrochloride in rat and dog Title: Discontinuous distribution of N-oxidation of
dietary-derived trimethylamine in a british population Title: Modipafant, a new paf antagonist:
pharmacokinetics and disposition in rat, dog and man. Title: Use of site-specified tritium-labelling to
confirm the formation of 17-oxosparteine as a minor
urinary metabolite of sparteine in man. Title: Identification of major biliary and urinary
metabolites of ecabapide in rats. Volume:- 26 Issue:- 10 Publication Date : 8th October 1996 Title: Regulation of
constitutive rat hepatic cytochromes P450 by
3-methylcholanthrene Title: Expression of human cytochrome P450 1A1
(CYP1A1) in saccharomyces cerevisiae inhibits cell
division Title: S-Methylation of dietthyldithiocarbamic acid in
rat liver microsomes Authors: James.J Lipsky,
Jennifer.S Lill, Dennis.C Mays. Title: Characterization of brimonidine metabolism with rat, rabbit, dog, monkey and human liver fractions and rabbit liver aldehyde oxidase Authors: Andrew.A Acheampong, S. Lam, S Vekich, A Breau, J Usansky, D Tang-Lui, D Harcourt, S Munk, H Nguyen, M Gast, D.S Chien. Pages 1035-1055. Title: Intermolecular interactions of antimicrobial
fluoroquinolones with purified rat liver CYP1A2 studied
by proton nuclear magnetic resonance spectroscopy Title: Molecular modelling of CYP3A4 from an alignment
with CYP102: Identification of key interactions between
putative active site residues and CYP3A - specific
chemicals Title: Disposition in the rat of
[2-3H]-Trans-4-hydroxy-2-3-nonenal, a product of lipid
peroxidation Title: Pharmacokinetics of a series of
bis(methanesulphonamido-arylalkyl)amines in the beagle
dog Volume:- 26 Issue:- 11 Publication Date : 14th November 1996 Title: Design, production
and characterisation of antibodies discriminating between
the phenol-and monoamine-sulphating forms of human phenol
sulphotransferase Title: Gender differences in ethanol oxidation and
cytochrome P450 2E1 content and functions in hepatic
microsomes from alcohol-preferring and non-preferring
rats Title: In vitro and in vivo oxidative
biotransformation in the west-african dwarf goat (caprus
hircus aegagrus). Substrate activities and effects of
inducers Title: Effects of roxithromycin, erythromycin and
troleandomycin on their N-demethylation by rat and human
cytochrome P450 enzymes Title: Human liver microsomal diazepam metabolism
using cDNA-expressed cytochrome P450s: role of CYP2B6,
2C19 and the 3A subfamily. Title: Metabolism of several 14c-nonylphenol isomers by rainbow trout (Oncorhynchus mykiss): in vivo and in vitro microsomal metabolites Authors: John J. Lech, Kasem Nithipatikom, Aaron C. Meldahl. Pages 1167-1180. Title: Interleukin-1ß and interleukin-6 repress
clofibric acid induction of different P450 isoforms in
cultured fetal rat hepatocytes Title: Pharmacokinetics of ethylene glycol Volume:- 26 Issue:- 12 Publication Date : 19th December 1996 Title: Biotransformation
and detoxificatio of insecticidal metyrapone analogues by
carbonl reduction in the human liver Title: Inhibition of tolbutamide 4-methylhydroxylation
by a series of non-steroidal anti-inflammatory drugs in
V79-NH cells expressing human cytochrome P4502C10 Title: Dietry modulation of human platelet phenolsulphotransferase activity Authors: R.H. Waring, R.M Harris. Pages 1241-1247. Title: (s)-4'-hydroxypropranolol causes product
inhibition and dose-dependent bioavailability of
propranolol enantiomers in the isolated perfused rat
liver and in rat liver microsomes. Title: Biotransformation of diethenylbenzenes, V.
Identification of urinary metaboloics of 1,
2-diethenylbenzene in the rat Title: The absorption, pharmacokinetics and metabolism
of 14C-Sumatriptan following intranasal administration to
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